INTERMACS classification for advanced heart failure

INTERMACS classification for advanced heart failure INTERMACS classification for advanced heart failure was developed as a sub classification for advanced heart failure, typically for those in advanced NYHA (New York Heart Association) Functional Class III and IV. Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) developed this classification with seven clinical profiles and an arrhythmia modifier [1].  This was to allow optimal selection of patients for medical and pacing therapies, cardiac transplantation and mechanical circulatory support. They found that 80% of current devices are being used in 2 profiles with the highest level of clinical compromise. Two modifiers were added for those on temporary circulatory support devices in the hospital and for frequent rehospitalization of patients being treated at home. So finally it became 7 profiles and 3 modifiers. Unlike in the usual types of classifications, in the INTERMACS classification, profile 1 is the most severe. It is critical cardiogenic shock with life threatening hypotension despite escalating inotropic support, with critical organ hypoperfusion. This is associated with worsening acidosis and/or lactate levels. This has been called “Crash and burn”. Profile 2 is one of progressive decline with declining function despite intravenous inotropic support with worsening renal function, nutritional depletion and inability to restore volume balance. This profile has been nicknamed &...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs