Function and expression of ATIP and its variants in cardiomyoblast cell line H9c2

Conclusions:
Previously ATIP has been shown to inhibit growth factor signalling in cancerous cells via an interaction with the AT2-receptor. This is the first report to identify that ATIP may have a similar role in other disease states characterised by excessive growth and indicates that for ATIP3, at least, an interaction with the AT2-receptor may not be necessary.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - March 2, 2015 Category: Biomedical Science Authors: Varghayee, N., Krezel, M. A., Rezmann, L., Chow, L., Frauman, A. G., Louis, W. J., Louis, S. N. Tags: Original Articles Source Type: research