Transplantation of periaortic adipose tissue from angiotensin receptor blocker-treated mice markedly ameliorates atherosclerosis development in apoE-/- mice

Conclusions:
Our findings demonstrated that AT1 receptor plays a crucial role in HCD-induced phenotypic alterations of tPAT, modulation of which could exert beneficial effects on atherosclerosis.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - March 2, 2015 Category: Biomedical Science Authors: Irie, D., Kawahito, H., Wakana, N., Kato, T., Kishida, S., Kikai, M., Ogata, T., Ikeda, K., Ueyama, T., Matoba, S., Yamada, H. Tags: Original Articles Source Type: research