Angiotensin II, via angiotensin receptor type 1/nuclear factor-{kappa}B activation, causes a synergistic effect on interleukin-1-{beta}-induced inflammatory responses in cultured mesangial cells

Conclusions:
These data indicates that Ang II, via AT1/NF-B pathway activation, cooperates with IL-β to increase the inflammatory response in mesangial cells.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - March 2, 2015 Category: Biomedical Science Authors: Alique, M., Sanchez-Lopez, E., Rayego-Mateos, S., Egido, J., Ortiz, A., Ruiz-Ortega, M. Tags: Original Articles Source Type: research