Carbonylation of Alkyl Radicals Derived from Organosilicates through Visible ‐Light Photoredox Catalysis

AngewchemCarbonylation of Alkyl Radicals Derived from Organosilicates through Visible ‐Light Photoredox CatalysisAlex Cartier, Etienne Levernier, Dr. Vincent Corc é, Prof. Takahide Fukuyama, Dr. Anne‐Lise Dhimane, Dr. Cyril Ollivier, Prof. Ilhyong Ryu, Prof. Louis Fensterbank Advocating a regime change: Primary, secondary, and tertiary alkyl radicals, formed by the photocatalyzed oxidation of organosilicates, underwent three ‐component reactions with carbon monoxide (CO) and radical acceptors to provide unsymmetrical ketones (see scheme). The concept of radical carbonylation under a photooxidative regime and metal‐free conditions has significant potential more generally for photocatalytic carbonylation reactions .
Source: Organometallic Current - Category: Chemistry Tags: Carbonylation Photoredox Catalysis Visible light Source Type: blogs