Charlson Comorbidity Index Guides Treatment Decisions for HER2 Positive Breast Cancer in Older Women

Woman,over age 70, compose 30% of breast cancer cases. Over expression of HER2 occurs in 15% of cases. NCCN guidelines recommend systemic treatment for tumors over 1 cm. The Charlson Comorbidity Index can quantify multiple comorbidities and predict a limited life expectancy that allows stratification of women over age 70 who may not benefit from systemic treatment of HER2 breast cancer.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Geriatric and Palliative Care Source Type: research