Transcriptional Response of Aged Skeletal Muscle to Aerobic Exercise

Exercise is beneficial for skeletal muscle functions across all ages. However, the response to exercise shifts with aging, resulting in anabolic resistance and limited gain in muscle strength and endurance. These changes likely reflect age-related alterations in transcriptional response underlying the muscular adaptation to exercise. The exact changes in gene expression accompanying exercise are largely unknown, and elucidating them is of a great clinical interest for optimizing the exercise-based therapies for sarcopenia.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Geriatric and Palliative Care Source Type: research