Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons

Conclusions:
These data indicate the important roles of peripherally-derived artemin on the regulation of TRPV1/A1 in DRG neurons in pathological conditions such as inflammatory and neuropathic pain.

Source: Molecular Pain - March 8, 2015 Category: Molecular Biology Authors: Yasuko Ikeda-MiyagawaKimiko KobayashiHiroki YamanakaMasamichi OkuboShenglan WangYi DaiHideshi YagiMunetaka HiroseKoichi Noguchi Source Type: research