Decompensation in advanced non-alcoholic fatty liver disease may occur at lower hepatic venous pressure gradient levels that in patients with viral disease

Portal hypertension (PH) is the strongest predictor of hepatic decompensation and death in patients with cirrhosis. However, its discriminatory accuracy in patients with non-alcoholic fatty liver disease (NAFLD) has been challenged as hepatic vein catheterization may not reflect the real portal vein pressure as accurately as in patients with other etiologies. We aimed to evaluate the relationship between hepatic venous pressure gradient (HVPG) and presence of portal hypertension related decompensation in patients with advanced NAFLD (aNAFLD).

Source: Clinical Gastroenterology and Hepatology - October 20, 2021 Category: Gastroenterology Authors: Octavi Bassegoda, Pol Olivas, Laura Turco, Mattias Mandorfer, Miquel Serra-Burriel, Luis Tellez, Wilhelmus Kwanten, Alexia Laroyenne, Oana Farcau, Edilmar Alvarado, Lucile Moga, Elise Vuille-Lessard, Jose Ignacio Fortea, Luis Iba ñez, Giulia Tosetti, Tho Source Type: research