What is the threshold of mature oocytes to obtain at least one healthy transferable cleavage-stage embryo after preimplantation genetic testing for fragile X syndrome?

This study is retrospective, analyzing a limited number of cycles. Moreover, the patients who were included in a fresh PGT cycle were selected on ovarian reserve parameters and show high values in ovarian reserve tests. This information could influence our conclusion.WIDER IMPLICATIONS OF THE FINDINGSThe results relate only to the target population of this study, with a correct ovarian reserve of AMH>1 and AFC>10. However, the information provided herein extends knowledge about the current state of COS forFMR1 mutation carriers in order to provide patients with proper counseling regarding the optimal number of oocytes needed to have a chance of transferring an unaffected embryo following PGT.STUDY FUNDING/COMPETING INTEREST(S)None.TRIAL REGISTRATION NUMBERN/A.
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research