The IgE response to Ascaris molecular components is associated with clinical indicators of asthma severity

Conclusions In this tropical population, IgE sensitization to Ascaris and the cross-reactive tropomyosins was frequent and associated with clinical indicators of asthma severity. The significant relationship between sensitization to the nematode-specific marker Asc s 1 and ER attendance supports these findings. Moreover, ascariasis increases the human IgE responses to HDM specific allergens.
Source: World Allergy Organization Journal - Category: Allergy & Immunology Source Type: research