Temperature Oscillations Drive Cycles in the Activity of MMP-2,9 Secreted by a Human Trabecular Meshwork Cell Line [Physiology and Pharmacology]

Conclusions.
Physiologically relevant temperature oscillations drive fluctuations of secreted MMP-2 and MMP-9 activity in hTM5 cells independent of peripheral clock genes and temperature-sensitive TRP channels.

Source: Investigative Ophthalmology - February 25, 2015 Category: Opthalmology Authors: Li, S. K.-l., Banerjee, J., Jang, C., Sehgal, A., Stone, R. A., Civan, M. M. Tags: Physiology and Pharmacology Source Type: research