Assessment of Retinal Function and Morphology in Aging Ccl2 Knockout Mice [Retinal Cell Biology]

Conclusions.
These data show that Ccl2 is important for preserving RPE and glial morphology with age, yet retinal function and gross morphology are maintained. Altered signaling in this chemokine pathway may, however, increase RPE and retinal vulnerability to disease.

Source: Investigative Ophthalmology - February 19, 2015 Category: Opthalmology Authors: Vessey, K. A., Waugh, M., Jobling, A. I., Phipps, J. A., Ho, T., Trogrlic, L., Greferath, U., Fletcher, E. L. Tags: Retinal Cell Biology Source Type: research