Factors Associated With Persistent Subfoveal Fluid and Complete Macular Hole Closure in the PIONEER Study [Retina]

Conclusions.
Persistent subfoveal fluid following MH surgery is a common finding that appears to delay visual recovery but not effect final visual outcome. The incidence of persistent subfoveal fluid appears to be related to intraoperative alterations after ILM peeling in the outer retinal architecture (e.g., increased EZ-RPE height and SRHR width). This finding suggests a novel mechanism for facilitating MH closure through ILM peeling (e.g., altering photoreceptor/RPE adherence and increasing retinal mobility that allows for complete hole closure).

Source: Investigative Ophthalmology - February 13, 2015 Category: Opthalmology Authors: Ehlers, J. P., Itoh, Y., Xu, L. T., Kaiser, P. K., Singh, R. P., Srivastava, S. K. Tags: Retina Source Type: research