Complex I Subunit Gene Therapy With NDUFA6 Ameliorates Neurodegeneration in EAE [Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology]

Conclusions.
NDUFA6 gene therapy provided long-term suppression of neurodegeneration in the EAE animal model suggesting that it may also ameliorate the mitochondrial dysfunction associated with permanent disability in optic neuritis and MS patients.

Source: Investigative Ophthalmology - February 13, 2015 Category: Opthalmology Authors: Talla, V., Koilkonda, R., Porciatti, V., Chiodo, V., Boye, S. L., Hauswirth, W. W., Guy, J. Tags: Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology Source Type: research