Degeneration and Regeneration of Corneal Nerves in Response to HSV-1 Infection [Cornea]

Conclusions.
Corneal sensory nerves were lost, consistent with loss of corneal sensation at day 8 pi. At day 30 pi, the cornea reinnervated but without recovering the normal arrangement of its fibers or function. SEMA 7A expression was increased at day 8pi, likely as part of a nerve regeneration mechanism.

Source: Investigative Ophthalmology - February 13, 2015 Category: Opthalmology Authors: Chucair-Elliott, A. J., Zheng, M., Carr, D. J. J. Tags: Cornea Source Type: research