Canonical/{beta}-Catenin Wnt Pathway Activation Improves Retinal Pigmented Epithelium Derivation From Human Embryonic Stem Cells [Nanotechnology and Regenerative Medicine]

Conclusions. Our findings demonstrated the importance of canonical/β-catenin Wnt signaling in RPE differentiation and showed that manipulating the pathway significantly improves RPE derivation from hESC.

http://www.iovs.org/cgi/content/full/56/2/1002?rss=1

Source: Investigative Ophthalmology - February 11, 2015 Category: Opthalmology Authors: Leach, L. L., Buchholz, D. E., Nadar, V. P., Lowenstein, S. E., Clegg, D. O. Tags: Nanotechnology and Regenerative Medicine Source Type: research