Angiotensin II as a Morphogenic Cytokine Stimulating Fibrogenesis of Human Tenon's Capsule Fibroblasts [Glaucoma]

Conclusions.
Our results show that trabeculectomy alter the levels of Ang II and its receptors in Tenon's capsule fibroblasts, and that Ang II increase HTFs proliferation, migration, and phenotype transition, suggesting that Ang II may play a role in wound healing after trabeculectomy.

Source: Investigative Ophthalmology - February 5, 2015 Category: Opthalmology Authors: Shi, H., Zhang, Y., Fu, S., Lu, Z., Ye, W., Xiao, Y. Tags: Glaucoma Source Type: research