Comparative transcriptome profiling in human bicuspid aortic valve disease using RNA sequencing

In conclusion, diverging molecular mechanisms underpin phenotype heterogeneity of valvular degeneration in BAV and data from the present study suggest that there may be shared mechanisms leading to calcification in BAV and TAV. Recognition of these pathways is fundamental to improve our understanding of the molecular basis of human BAV disease.
Source: Physiological Genomics - Category: Genetics & Stem Cells Authors: Tags: Omics Technologies and Applications Source Type: research