Deficiency of PPAR γ in Bone Marrow Stromal Cells Does not Prevent High-Fat Diet-Induced Bone Deterioration in Mice

ConclusionsThese data indicate that PPAR γ has site-specific impacts on bone structures in mice and that knockout PPARγ in BMSC increased bone mass (BV/TV) in the tibia but not the lumbar vertebrae. PPARγ disruption in BMSC did not prevent HF diet–induced bone deterioration in mice.
Source: Journal of Nutrition - Category: Nutrition Source Type: research