Risk for Post-Colonoscopy Irritable Bowel Syndrome in Patients with and without Antibiotic Exposure: A Retrospective Cohort Study

Laboratory studies have demonstrated that antibiotic use in conjunction with bowel purgatives causes alterations to the gut microbiota. Because gut microbiota changes may be a trigger for the development of irritable bowel syndrome (IBS), we sought to assess whether individuals who undergo bowel cleansing for colonoscopy and have concurrent antibiotic exposure develop IBS at higher rates than individuals who undergo colonoscopy without antibiotic exposure.

Source: Clinical Gastroenterology and Hepatology - September 2, 2021 Category: Gastroenterology Authors: Ravy K. Vajravelu, Jordan M. Shapiro, Josephine Ni, Shivani U. Thanawala, James D. Lewis, Hashem B. El-Serag Source Type: research