Adjuvant chemoradiation may improve survival over adjuvant chemotherapy in resected pancreatic cancer patients who are high risk for locoregional recurrence

Conclusion Adjuvant chemoradiation significantly decreases LRR in resected pancreatic cancer patients compared to adjuvant chemotherapy. Significant predictors of survival on MVA were LRR and N-category. Additionally on subgroup analysis, chemoradiation improved survival over chemotherapy with a (1) positive surgical margin and/or (2) LNR ≤0.2 with ≥8 LNs dissected.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research