Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system

ConclusionSIRT5 promotes arterial thrombosis by modulating fibrinolysis through endothelial PAI-1 expression. Hence, SIRT5 may be an interesting therapeutic target in the context of atherothrombotic events.
Source: Cardiovascular Research - Category: Cardiology Source Type: research