Nasopharyngeal carcinoma – A review

Globally, there are approximately 80,000 new cases of nasopharyngeal carcinoma (NPC) per annum and circa 50,000 patients die from this neoplasm annually. The first series of patients with NPC was published in 1901 and comprised 14 patients.1 A subsequent and larger study was published in 1922 and comprised 79 patients2, followed by a large and comprehensive study in 1941 of the clinicopathologic features in 114 patients.3 Currently WHO classifies nasopharyngeal carcinoma (NPC) into keratinizing (K) carcinoma (squamous cell carcinoma – SCC), non-keratinizing (NK) carcinoma, including differentiated and undifferentiated variants and basaloid SCC.
Source: Seminars in Diagnostic Pathology - Category: Pathology Authors: Source Type: research