Oral administration of dextran sodium sulphate induces a caecum‐localized colitis in rabbits

We describe a reproducible and reliable rabbit model of DSS colitis. Localization of the inflammation in the caecum and its similarities to IBD make this model particularly suitable to study TSO therapy in vivo.

Source: International Journal of Experimental Pathology - February 1, 2015 Category: Pathology Authors: Irina Leonardi, Flora Nicholls, Kirstin Atrott, Alexandra Cee, Bernhard Tewes, Roland Greinwald, Gerhard Rogler, Isabelle Frey‐Wagner Tags: Original Article Source Type: research