In vitro fertilization embryo development from caffeine-treated murine sperm

Conclusions
Caffeine treatment affected body weight of male mice. However, testicular weight, histological features and total blood testosterone concentration were not statistically different. In addition, following IVF using sperm from these mice, blastocyst formation decreased in a dose-dependent manner. These findings suggest that embryo development from oocytes fertilized with sperm from caffeine-administered male mice is negatively affected.

Source: Reproductive Medicine and Biology - February 26, 2015 Category: OBGYN Source Type: research