Goldenhar syndrome

Publication date: Available online 25 February 2015 Source:Apollo Medicine Author(s): Reena Sethi , Arun Sethi , Parul Lokwani , Manisha Chalwade Goldenhar syndrome, a term that is often used synonymously with “Oculo-Auriculo-Vertebral (OAV) spectrum”, is a rare disorder that is apparent at birth (congenital).1,5,6 The disorder is characterized by a wide spectrum of symptoms and physical features that may vary greatly in range and severity from case to case. However, such abnormalities tend to involve the cheekbones, jaws, mouth, ears, eyes and/or bones of the spinal column (vertebrae).1,6 Although, in most cases, such malformations affect one side of the body (unilateral), approximately 10–33 per cent of affected individuals have such malformations on both sides of the body (bilateral), with one side typically more affected than the other (asymmetry). In the majority of such cases, the right side is more severely affected than the left.1,7,8

Source: Apollo Medicine - February 26, 2015 Category: Journals (General) Source Type: research