Colony Stimulating Factors 1, 2, 3 and early pregnancy steps: from bench to bedside

The colony-stimulating factor (CSF) family includes: CSF-1 or macrophage colony-stimulating factor (M-CSF), CSF-2 or granulocyte macrophage colony-stimulating factor (GM-CSF), and CSF-3 or granulocyte colony-stimulating factor (G-CSF). CSFs are 18- to 70-kDa labile glycoproteins and act through specific membrane receptors, via JAK-STAT signalling pathways in an endocrine, paracrine or autocrine model (Metcalf, 2010).

Source: Journal of Reproductive Immunology - February 10, 2015 Category: Allergy & Immunology Authors: Mona Rahmati, Marie Petitbarat, Sylvie Dubanchet, Armand Bensussan, Gerard Chaouat, Nathalie Ledee Tags: Review Source Type: research