Application of Gap-Constraints Given Sequential Frequent Pattern Mining for Protein Function Prediction

Predicting protein function from protein-protein interaction network is challenging due to its complexity and huge scale of protein interaction process along with inconsistent pattern. Previously proposed methods such as neighbor counting, network analysis and graph pattern mining has predicted functions by calculating the rules and probability of patterns inside network. Although these methods have shown good prediction, difficulty still exist in searching several functions which are exceptional from simple rules and patterns as a result of not consider the inconsistent part of interaction network.

Source: Osong Public Health and Research Perspectives - February 23, 2015 Category: Global & Universal Authors: Hyeon Ah Park, Taewook Kim, Meijing Li, Ho Sun Shon, Jeong Seok Park, Keun Ho Ryu Tags: Original Article Source Type: research