RANK-ligand (RANKL) expression in young breast cancer patients and during pregnancy
We examined the difference in expression of RANK/RANKL between pregnant and non-pregnant patients and their association with clinicopathological features and prognosis. We also evaluated genes and pathways associated with RANK/RANKL expression on primary tumors.
Results:
RANKL but not RANK expression was more prevalent in the pregnant group, both on the tumor and adjacent normal tissue, independent of other clinicopathological factors (both P
Source: Breast Cancer Research - Category: Cancer & Oncology Authors: Hatem AzimFedro PeccatoriSylvain BrohéeDaniel BranstetterSherene LoiGiuseppe VialeMartine PiccartWilliam DougallGiancarlo PruneriChristos Sotiriou Source Type: research
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