Transcriptome and proteome mapping in the sheep atria reveal molecular featurets of atrial fibrillation progression

ConclusionsTranscriptomic and proteomic analysis of AF progression in a large animal model shows that significant changes occur at early stages, and that among others involve previously undescribed increase in mitochondria, changes to the chromatin of atrial CMs, and genes related to neural function and cell proliferation.
Source: Cardiovascular Research - Category: Cardiology Source Type: research