Characterization in mice of the resident mesenchymal niche maintaining AT2 stem cell proliferation in homeostasis and disease

In conclusion, rMC-Sca1PosFgf10Pos cells play important role in supporting AT2 stem cells proliferation and differentiation. This result sheds a new light on the subpopulations of rMCs contributing to the AT2 stem cell niche in homeostasis and in the context of pre-existing metabolic diseases.

Source: Stem Cells - June 16, 2021 Category: Stem Cells Authors: Sara Taghizadeh, Monika Heiner, Ana Ivonne Vazquez ‐Armendariz, Jochen Wilhelm, Susanne Herold, Chengshui Chen, Jin San Zhang, Saverio Bellusci Tags: Tissue ‐Specific Stem Cells Source Type: research