Effects of medetomidine and xylazine on intraocular pressure and pupil size in healthy Beagle dogs

Conclusions and clinical relevanceLow or moderate doses of medetomidine or xylazine did not induce significant changes in IOP or pupil size. In contrast, high doses of medetomidine or xylazine induced significant changes up to 8 hours after treatment, but values remained within the normal canine physiological range. The results of this study suggest a lack of significant change in IOP and pupil size in healthy dogs administered low or moderate doses of xylazine or medetomidine.

Source: Veterinary Anaesthesia and Analgesia - January 1, 2015 Category: Veterinary Research Authors: Teppei Kanda, Ayano Iguchi, Chieko Yoshioka, Haruka Nomura, Kanako Higashi, Minami Kaya, Rie Yamamoto, Tomoko Kuramoto, Toshinori Furukawa Tags: Short Communication Source Type: research