Biology of Hypoxia

There is an important and strong, but complex influence of the tumor microenvironment on tumor cells׳ phenotype, aggressiveness, and treatment sensitivity. One of the most frequent and best-studied aspects of the tumor microenvironment is hypoxia. Low oxygen tension often occurs in tumor cells by several mechanisms, for example, poor angiogenesis and increased oxygen consumption. Hypoxia is a heterogeneous concept with oxygen tensions ranging from
Source: Seminars in Nuclear Medicine - Category: Nuclear Medicine Authors: Source Type: research