Mechanism of the development of nonalcoholic steatohepatitis after pancreaticoduodenectomy

Conclusions Enhanced FA uptake into hepatocytes and lipogenesis, up-regulation of PPARγ, and disruption of VLDL excretion into the circulation are possible mechanisms of steatogenesis after PD. General Significance These results provide a basis for understanding the pathogenesis of NAFLD/NASH following PD.
Source: BBA Clinical - Category: Biochemistry Source Type: research