Comparison of Monte Carlo with pencil beam dosimetry for lung CyberKnife SBRT, correlation with local recurrence

Conclusions Without the use of MC planning, target structures were substantially underdosed. Local failures were associated with PTVmicro undercoverage, which suggests delivering a therapeutic dose to this expanded microscopic disease target volume is beneficial. MC dosimetry is preferable for lung SBRT, while the PB algorithm was adequate for predicting pulmonary toxicity.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research