Estradiol prevented intestinal ischemia and reperfusion-induced changes in intestinal permeability and motility in male rats

CONCLUSION: Collectively, our findings indicate that estradiol treatment can modulate the deleterious intestinal effects of I/R injury. Thus, estradiol mediates the improvement in gut barrier functions and prevents intestinal dysfunction, which may reduce the systemic inflammatory response.
Source: Clinics - Category: General Medicine Source Type: research