Androgen Plays a Carcinogenic Role in EOC via the PI3K/AKT Signaling Pathway in an AR-Dependent Manner

Conclusion: We showed that testosterone was able to promote the proliferation of ovarian cancer cells through activating the PI3K/AKT signaling pathway in an AR dependent manner and AR may be a screening indicator for anti-androgen therapy sensitive cases of EOC.

Source: Journal of Cancer - April 19, 2021 Category: Cancer & Oncology Authors: Yanfang Li, Sha Li, Yizhou Zhang, Shuhong Shi, Shan Qin, Chang Wang, Juan Du, Jingle Ma, Huan Chen, Huixian Cui Tags: Research Paper Source Type: research