Syntaxin 2 promotes colorectal cancer growth by increasing the secretion of exosomes

Conclusions: Our data provide evidence that STX2 promotes CRC growth by increasing exosomes secretion of CRC cells; And the modulation of STX2 in exosomes secretion correlates with Rab8a. Thus, our study identified a new mechanism of STX2 in CRC growth and may provide a possible strategy for CRC therapy.

Source: Journal of Cancer - April 19, 2021 Category: Cancer & Oncology Authors: Yongxia Wang, Yongzhen Li, Hong Zhou, Xinlai Qian, Yuhan Hu Tags: Research Paper Source Type: research