Cancer-associated fibroblasts in gastric cancer affect malignant progression via the CXCL12-CXCR4 axis

Conclusion: High expression of CXCL12 in CAFs in a GC microenvironment can affect the migration, invasion, and EMT of GC cells. Furthermore, it can cause poor prognosis in patients with GC.

Source: Journal of Cancer - April 19, 2021 Category: Cancer & Oncology Authors: Yan Qin, Fang Wang, Hengli Ni, Yao Liu, Yuan Yin, Xinyi Zhou, Guihua Gao, Qing Li, Xiaowei Qi, Jianming Li Tags: Research Paper Source Type: research