Increased tumor-infiltrating plasmacytoid dendritic cells promote cancer cell proliferation and invasion via TNF- α /NF- κ B/CXCR-4 pathway in oral squamous cell carcinoma

Conclusions: Tumor-infiltrating pDC promoted oral cancer proliferation and invasion via activating the TNF-α/NF-κB/CXCR-4 pathway, which may serve as a potential immunological target for the treatment of OSCC in the future.

Source: Journal of Cancer - April 19, 2021 Category: Cancer & Oncology Authors: Nannan Han, Xing Li, Yupu Wang, Lin Wang, Chunye Zhang, Zun Zhang, Min Ruan, Chenping Zhang Tags: Research Paper Source Type: research