High expression of TREM2 promotes EMT via the PI3K/AKT pathway in gastric cancer: bioinformatics analysis and experimental verification

Conclusions: We identified some important genes associated with the progression of GC via public database analysis, explored and verified the effects of proto-oncogene TREM2 on EMT via the PI3K/AKT pathway. TREM2 may be a novel target in the GC therapy.

Source: Journal of Cancer - April 19, 2021 Category: Cancer & Oncology Authors: Chunmei Li, Xiaoming Hou, Shuqiao Yuan, Yigan Zhang, Wenzhen Yuan, Xiaoguang Liu, Juan Li, Yuping Wang, Quanlin Guan, Yongning Zhou Tags: Research Paper Source Type: research