Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells

Conclusions: SPN-A566V, or other equivalent mutations, could be late events that promote tumor progression by increasing the CSC pool and, eventually, the malignant behavior of the tumor.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Eva M Verdugo-Sivianes, Ana M Rojas, Sandra Mu ñ oz-Galv á n, Daniel Otero-Albiol, Amancio Carnero Tags: Research Paper Source Type: research