The immune contexture of primary central nervous system diffuse large B cell lymphoma associates with patient survival and specific cell signaling

Conclusion: Altogether, our study reveals that patient stratification according to immune subtypes, HLA status, and immune checkpoint molecule quantification should be considered prior to immune checkpoint inhibitor therapy. Moreover, TIM-3 protein should be considered an axis for future therapeutic development.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Melissa Alame, Emmanuel Cornillot, Val è re Cacheux, Val é rie Rigau, Val é rie Costes-Martineau, Vanessa Lacheretz-Szablewski, Jacques Colinge Tags: Research Paper Source Type: research