MiR-22 modulates brown adipocyte thermogenesis by synergistically activating the glycolytic and mTORC1 signaling pathways

Conclusions: Our findings identify miR-22 as a critical regulator in the control of thermogenesis in BAT and as a potential therapeutic target for human metabolic disorders.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Pengbo Lou, Xueyun Bi, Yuhua Tian, Guilin Li, Qianqian Kang, Cong Lv, Yongli Song, Jiuzhi Xu, Xiaole Sheng, Xu Yang, Ruiqi Liu, Qingyong Meng, Fazheng Ren, Maksim V. Plikus, Bin Liang, Bing Zhang, Huiyuan Guo, Zhengquan Yu Tags: Research Paper Source Type: research