Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis

Conclusions: Our findings implicate GzmA as a key regulator of the inflammatory response during abdominal sepsis and provide solid evidences about its therapeutic potential for the treatment of this severe pathology.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Marcela Garz ó n-Titua ñ a, Jos é L Sierra-Monz ó n, Laura Comas, Llipsy Santiago, Tatiana Khaliulina-Ushakova, Iratxe Uranga-Murillo, Ariel Ramirez-Labrada, Elena Tapia, Elena Morte-Romea, Sonia Algarate, Ludovic Couty, Eric Camerer, Phillip I Bird, Tags: Research Paper Source Type: research