Engineering extracellular vesicles with platelet membranes fusion enhanced targeted therapeutic angiogenesis in a mouse model of myocardial ischemia reperfusion

Conclusions: This engineering strategy to modify pre-isolated EVs with platelet membranes by membrane fusion bestows EVs with the targeting ability of platelets and offers an exciting opportunity to design other targeted EVs fused with cell membranes from different sources for therapeutic angiogenesis.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Qiyu Li, Yanan Song, Qiaozi Wang, Jing Chen, Jinfeng Gao, Haipeng Tan, Su Li, Yuan Wu, Hongbo Yang, Hanwei Huang, Yang Yu, Yao Li, Ning Zhang, Zheyong Huang, Zhiqing Pang, Juying Qian, Junbo Ge Tags: Research Paper Source Type: research