miR-375 prevents high-fat diet-induced insulin resistance and obesity by targeting the aryl hydrocarbon receptor and bacterial tryptophanase (tnaA) gene

Conclusion: Collectively our findings reveal that oral administration of GDNP to HFD mice improves host glucose tolerance and insulin response via regulating AhR expression by GDNP induced miR-375 and VAMP7.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Anil Kumar, Yi Ren, Kumaran Sundaram, Jingyao Mu, Mukesh K Sriwastva, Gerald W Dryden, Chao Lei, Lifeng Zhang, Jun Yan, Xiang Zhang, Juw Won Park, Michael L Merchant, Yun Teng, Huang-Ge Zhang Tags: Research Paper Source Type: research