A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis

Conclusions: The present findings uncovered a novel pro-EndMT mechanism during the pathogenesis of diabetic cardiac fibrosis via the upregulation of KLK8, and may contribute to the development of future KLK8-based therapeutic strategies for diabetic cardiomyopathy.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Jian-Kui Du, Qing Yu, Yu-Jian Liu, Shu-Fang Du, Li-Yang Huang, Dan-Hong Xu, Xin Ni, Xiao-Yan Zhu Tags: Research Paper Source Type: research