Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid- β -induced neurotoxicity

Conclusion: Our results imply that US-HA-Exo have the potential to provide neuroprotective effects to reverse oligomeric amyloid-β-induced cytotoxicity in vitro and, when combined with FUS-induced BBB opening, enable the clearance of amyloid-β plaques in vivo.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Zhiting Deng, Jieqiong Wang, Yang Xiao, Fei Li, Lili Niu, Xin Liu, Long Meng, Hairong Zheng Tags: Research Paper Source Type: research